FK AS Trencin is gekwalificeerd voor de 2e Kwalificatieronde Champions League 2016/2017.
SK Slovan Bratislava, Spartak Myjava en FC Spartak Trnava zijn geplaatst voor de 1e Kwalificatieronde Europa League 2016/2017.
MFK Skalica is gedegradeerd naar de Slowaakse 2. Liga 2016/2017.
Slowaakse Fortuna Liga 2015/2016
| Pos | Club | P | W | D | L | F | A | GD | Pts |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  FK AS Trenčín | 33 | 26 | 3 | 4 | 73 | 28 | 45 | 81 |
| 2 |  ŠK Slovan Bratislava | 33 | 20 | 9 | 4 | 50 | 25 | 25 | 69 |
| 3 |  Spartak Myjava | 33 | 18 | 6 | 9 | 41 | 33 | 8 | 60 |
| 4 |  FC Spartak Trnava | 33 | 16 | 6 | 11 | 49 | 41 | 8 | 54 |
| 5 |  MŠK Žilina | 33 | 14 | 6 | 13 | 58 | 46 | 12 | 48 |
| 6 |  MFK Ružomberok | 33 | 12 | 9 | 12 | 42 | 41 | 1 | 45 |
| 7 |  FC DAC 1904 Dunajská Streda | 33 | 12 | 7 | 14 | 38 | 42 | -4 | 43 |
| 8 |  FO ŽP Šport Podbrezová | 33 | 10 | 7 | 16 | 43 | 46 | -3 | 37 |
| 9 |  FC ViOn Zlaté Moravce | 33 | 7 | 10 | 16 | 38 | 57 | -19 | 31 |
| 10 |  FK Senica | 33 | 7 | 9 | 17 | 30 | 48 | -18 | 30 |
| 11 |  MFK Zemplín Michalovce | 33 | 7 | 8 | 18 | 32 | 55 | -23 | 29 |
| 12 |  MFK Skalica | 33 | 6 | 6 | 21 | 30 | 62 | -32 | 24 |